This Alcohol Withdrawal Timeline depicts the total duration of the alcohol withdrawal process. Many people stop feeling the effects of alcohol withdrawal four to five days after their last drink. Symptoms are generally at their worst on the third day. If you decide to stop drinking regularly and heavily, you will most likely experience withdrawal symptoms. As shown in this Alcohol Withdrawal Timeline, the time it takes to detox depends on several factors, such as how much you drink, how long you have been drinking, and whether you've previously experienced alcohol withdrawal.